Product name: Folinic acid calcium salt hydrate

CAS Number: 1492-18-8

Molecular formula: C20H21CaN7O7

Molecular weight: 511.50100

Appearance & Property: Yellow crystalline powder

Solubility: soluble in water, almost insoluble in ethanol or ether; soluble in 0.1mol/L sodium hydroxide solution

Melting point: 240-250ºC

Mainly used as an antidote for folic acid antagonists (such as methotrexate, pyrimethamine or trimethoprim, etc.).

It is used to prevent severe toxic effects caused by methotrexate overdose or high-dose treatment.

Megaloblastic anemia caused by folic acid deficiency.

When combined with fluorouracil, it is used to treat advanced colon cancer and rectal cancer.